Key Takeaways
Results of a recent large umbrella review of meta-analyses revealed that omega-3 polyunsaturated fatty acids (PUFA) supplementation significantly improved depression symptoms in most studies.
Benefits of omega-3 PUFA supplementation was more pronounced in major depressive disorder (MDD).
More significant effects were seen when both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) was supplemented at an average dose of >3g/day for >15 weeks.
Mental health conditions continue to be on the rise, with over 1 in 5 Australian adults estimated to have experienced a mental disorder in the past 12 months. 1 Globally, depression is the most prevalent mental health condition across all age categories and is the leading cause of disability, incurring a significant emotional and economic burden.2 Around 280 million people are living with this debilitating condition, which is approximately 50% more prevalent in women.3 Alarmingly, almost 60% of people with depression do not seek medical support due to the fear and stigma around the condition. 4
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