Gut microbes with an increased capacity to metabolise carbohydrates may be hindering weight loss in overweight adults according to research from the US-based Mayo Clinic.
Researchers wanted to determine whether compositional and functional characteristics of the gut microbiota in adults predict responses to a comprehensive lifestyle intervention program in overweight and obese adults.
26 participants were recruited from the Mayo Clinic Obesity Treatment Research Program to participate in a lifestyle intervention program for weight loss. Faecal stool samples were obtained at baseline and after three months. Loss of at least five percent of baseline weight after three months was defined as success.