Elevated vitamin B6 levels and peripheral neuropathy

Key Takeaways

• Peripheral neuropathy (PN) can develop from both vitamin B6 deficiency and toxicity.
• PN occurs most commonly when multiple products containing vitamin B6 are taken, often unwittingly.
• PN occurs when supplementing with pyridoxine, the inactive form of vitamin B6.
• PN induced by vitamin B6 toxicity typically resolves within 6 months following cessation of supplements containing pyridoxine.