25 Feb 2016 Blackmores Institute Glucosamine chondroitin shows long term protection in knee oa 25 Feb 2016 Share Share on LinkedIn Share on Facebook Share on Twitter Share on Google+ Share on Pinterest News Long term treatment with a combination of chondroitin sulphate and glucosamine significantly reduces cartilage volume loss in patients with knee osteoarthritis, according to the results of a Canadian study. Moreover, retention of cartilage was related to exposure time to treatment during a period of 6 years. × To continue reading this article, please Log In or Sign Up for access.