14 Jul 2026 Kate Street (Clinical Nutritionist) Psychoneuroimmunology | Connecting the mind, brain, gut, and immune system 14 Jul 2026 Share Share on LinkedIn Share on Facebook Share on Twitter Share on Google+ Share on Pinterest Written by Kate Street, Clinical Nutritionist and Communications and Content Coordinator at Blackmores Institute Articles Key highlights Psychoneuroimmunology (PNI) explores the bidirectional interactions between psychological processes, the nervous system, and immune function. Stress signalling can influence immune balance through neuroendocrine pathways, including the HPA axis and sympathetic nervous system. The gastrointestinal tract and gut microbiome are important contributors to neuroimmune communication, linking microbial, immune, and neural signalling pathways. Emerging research is exploring how lifestyle factors and nutritional approaches may support immune resilience through these interconnected systems. × To continue reading this article, please Log In or Sign Up for access.