Level B/D - Human study. Study showed an anticoagulant effect at a dose of 3 g daily. In vitro study

Evidence suggests this interaction might occur in some patients

Clinical evaluation by a healthcare professional is recommended to assess the degree of intervention required

Anticoagulants and antiplatelet agents

Level B/D - Human studies/animal studies (hypotensive activity has been shown in animal studies but clinical effects are still unclear)

In vitro and/or animal evidence with unclear implications, however, it cannot exclude the possibility of occurring in humans

Intervention by a healthcare professional may be required

Antihypertensive drugs

Depending on drug and disease state

Animal studies (studies show that reishi decreases blood sugar, but clinical studies have failed to confirm this)